Anti-APC Monoclonal Antibody M00008 from BosterBio

Product Specs
ItemAnti-APC Monoclonal Antibody
CompanyBosterBio
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberM00008
Quantity100 µl
ApplicationsWB,IHC,ICC,IF,IP
FormatRabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA., Liquid
ReactivityHuman,Mouse,Rat
HostRabbit
ImmunogenA synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex
NCBI Full Gene NameAPC regulator of WNT signaling pathway
NCBI Gene AliasesBTPS2, DESMD, DP2, DP2.5, DP3, GS, PPP1R46
ClonalityMonoclonal
PurityAffinity-chromatography
Brand/TrademarkBosterbio
CloneFAD-1
Concentration0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure
Research AreaCancer, Cancer Susceptibility, Cardiogenesis, Cardiovascular, Cell Biology, Cell Cycle, Cell Division, Cell Type Marker, Cytoplasmic, Epigenetics And Nuclear Signaling, Neuroscience, Oncoproteins/Suppressors, Signaling Pathways, Spindle, Stem Cells, Transcription, Transcription Factors/Regulators, Tumor Suppressors
IsotypeIgG
StorageStore at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles
TargetAPC